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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SNRNP70 All Species: 18.18
Human Site: S226 Identified Species: 28.57
UniProt: P08621 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08621 NP_003080.2 437 51557 S226 Y D E R P G P S P L P H R D R
Chimpanzee Pan troglodytes XP_001156213 534 62599 S323 Y D E R P G P S P L P H R D R
Rhesus Macaque Macaca mulatta XP_001112732 579 66665 S368 Y D E R P G P S P L P H R D R
Dog Lupus familis XP_541503 439 51493 S226 Y D E R P G P S P L P H R D R
Cat Felis silvestris
Mouse Mus musculus Q62376 448 51974 S226 Y D E R P G P S P L P H R D R
Rat Rattus norvegicus Q5U1W5 244 29185 F90 V R D L V T G F S K G Y A F I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517310 232 27182 R77 K R R E K I E R R Q Q E V E T
Chicken Gallus gallus
Frog Xenopus laevis P09406 471 57185 R229 Y D E R D R E R E R D R R E R
Zebra Danio Brachydanio rerio Q4KMD3 208 24569 V54 D P D L T L F V A R L N P Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17133 448 52882 E225 E R E R Y R L E R E R E D R E
Honey Bee Apis mellifera XP_623789 450 53998 E225 E R E R Y R L E R E R E N S G
Nematode Worm Caenorhab. elegans Q10021 208 23961 D54 D A E D A C H D L D G K T M E
Sea Urchin Strong. purpuratus XP_001193416 500 59344 R225 N R E R E R E R E R E D E E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42404 427 50370 P261 Q S E E P S R P R E E R E K S
Baker's Yeast Sacchar. cerevisiae Q00916 300 34429 K146 V K D K I T Q K S K G Y A F I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.8 75.4 98.4 N.A. 95.3 27.9 N.A. 51.9 N.A. 67.5 23.7 N.A. 42.4 46.6 24.4 50
Protein Similarity: 100 81.8 75.4 98.8 N.A. 96.4 37 N.A. 52.6 N.A. 76.6 31.5 N.A. 57.1 59.7 32.7 61.6
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 0 N.A. 40 0 N.A. 13.3 13.3 6.6 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 6.6 N.A. 46.6 13.3 N.A. 13.3 13.3 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. 39.8 24.9 N.A.
Protein Similarity: N.A. N.A. N.A. 56.7 37 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 0 0 0 7 0 0 0 14 0 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 40 20 7 7 0 0 7 0 7 7 7 7 34 0 % D
% Glu: 14 0 74 14 7 0 20 14 14 20 14 20 14 20 14 % E
% Phe: 0 0 0 0 0 0 7 7 0 0 0 0 0 14 0 % F
% Gly: 0 0 0 0 0 34 7 0 0 0 20 0 0 0 7 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 34 0 0 0 % H
% Ile: 0 0 0 0 7 7 0 0 0 0 0 0 0 0 14 % I
% Lys: 7 7 0 7 7 0 0 7 0 14 0 7 0 7 0 % K
% Leu: 0 0 0 14 0 7 14 0 7 34 7 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % N
% Pro: 0 7 0 0 40 0 34 7 34 0 34 0 7 0 0 % P
% Gln: 7 0 0 0 0 0 7 0 0 7 7 0 0 7 0 % Q
% Arg: 0 34 7 60 0 27 7 20 27 20 14 14 40 7 40 % R
% Ser: 0 7 0 0 0 7 0 34 14 0 0 0 0 7 14 % S
% Thr: 0 0 0 0 7 14 0 0 0 0 0 0 7 0 14 % T
% Val: 14 0 0 0 7 0 0 7 0 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 40 0 0 0 14 0 0 0 0 0 0 14 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _